Enmity Against God

Ye adulterers and adulteresses, know ye not that the friendship of the world is enmity with God? whosoever therefore will be a friend of the world is the enemy of God.
- James 4:4 (KJV)

Satan uses the world to distance us from the Creator:

Satan doesn't come to us directly to tell us, "Stop enjoying Christ and serve me"! He puts on a mask, the world, which is a system that attracts us and captivates us in many ways, and through this system he keeps us away from God and the enjoyment of God. From behind the mask of the world and through the things of the world enjoyed by us, Satan injects death into us indirectly yet constantly.
- A God-Man

The flesh and the Spirit are at war:

Love not the world, neither the things that are in the world. If any man love the world, the love of the Father is not in him. For all that is in the world, the lust of the flesh, and the lust of the eyes, and the pride of life, is not of the Father, but is of the world.
- 1 John 2:15-16 (KJV)